Scientific Overview of CBRN
CBRN (chemical, biological, radiological or nuclear) research aims to identify protective or defense measures that can be applied in situations where advanced research and development of medical countermeasures are necessary.
Research conducted to characterize medical interventions for humans follow the FDA’s Animal Rule addressing efficacy using animal models for translation of disease manifestations and potential treatments.
Researchers are often interested in physiologic parameters to detect changes in fever, heart rate, respiration, sleep and seizure activities. Wireless physiological monitoring has established its position as a technology that enables researchers to acquire data on ambulatory animal models that closely represent human scenarios; thus, providing critical physiologic data not feasible via other methods.
Gathering data to aid in the development of defense countermeasures to preserve human life, is trusted to advanced technologies provided by DSI.
- Implantable telemetry increases safety for personnel by providing information remotely, and limiting human to subject interactions
- Plethysmography solutions help researchers understand potential side effects when respiratory airways airways are the focus of interest
Using DSI technologies, researchers safely collect data for a complete physiologic view of animal models and the impact to physiologic changes during these important studies.
Methods and Parameters
Physiologic data is critical to understanding disease morphology and physiologic response for the establishment of treatment regimens for chemical, biological, radiation and nuclear countermeasures.
Parameters Commonly Measured by CBRN Researchers include assessment of respiratory function. Implantable telemetry can be combined with chamber systems to collect cardiovascular, EEG, temperature, activity and respiratory function in a single system.