Hypertension

More than one billion people suffer from high blood pressure, putting them at greater risk for cardiovascular disease and stroke.

 

 

Hypertension is a condition in which blood pressure in the arteries is chronically elevated above normal levels.  Although high blood pressure does not typically display symptoms, hypertension is a major risk factor for coronary artery disease, stroke, heart failure, atrial fibrillation, peripheral vascular disease, vision loss, chronic kidney disease, and dementia.

 

1 in 3
Americans suffer from hypertension
>90%
of cases are related to lifestyle factors such as high salt diet, obesity, alcohol use, and smoking
3340
publications cite use of DSI technology on Google Scholar


 

 

Researchers studying hypertension investigate its causes and responses to potential treatments using a variety of animal models.  Academic researchers often utilize mice or rats to answer questions regarding the biological mechanisms of hypertension.  Canines and other species are used in safety evaluation of novel therapies due to the vascular and biological similarities to humans.
Transgenic-Mouse-Model


Wiggers Diagram, Blood pressure, Electrocardiogram, ECG, hypertension





Due to the complex nature of blood pressure control, multiple endpoints are of interest to researchers.  These include:

 

 

 

  • Blood Pressure

  • ECG

  • Baroreceptor Sensitivity

  • Pulse Wave Velocity

  • Renal Nerve Activity

  • Glucose

 

 

 

 

DSI offers a comprehensive line of telemetry implants capable of measuring pressure and biopotential endpoints in species ranging from mice to swine.

 

Learn more about the pressure sensing implants available from DSI.

DSI M series Website_Circle Image

 

 

Ponemah software is trusted by hypertension researchers around the world to reliably and accurately acquire and analyze physiologic endpoints.

 

Learn more about Ponemah software from DSI.

Ponemah BP Website_Circle Image