DSI Cardiovascular Safety Technology
DSI telemetry is completely implantable and designed for acquiring physiologic data from conscious, freely moving laboratory animals, reducing animal stress and ensuring the most reliable cardiovascular and/or other biopotential data. We offer a comprehensive line of telemetry implants capable of simultaneously measuring pressure, bioelectrical, temperature and activity endpoints in species ranging from mice to non-human primate.
The Power of Ponemah Software
Data collection and analysis for preclinical studies
Cardio-Oncology References Citing DSI Technology
Charych, D., Hoch, U., Langowski, J., Lee, S., Addepalli, M., Kirk, P., . . . Doberstein, S. (2016). NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(3), 680-90.
Collins, T., Gray, K., Bista, M., Skinner, M., Hardy, C., Wang, H., . . . Harmer, A. R. (2018). Quantifying the relationship between inhibition of VEGF receptor 2, drug-induced blood pressure elevation and hypertension. British Journal of Pharmacology, 175(4), 618-630. doi:10.1111/bph.14103
Kim, T., Kim, K., Seo, J., Park, S., & Henry, S. P. (2014). Antisense oligonucleotides on neurobehavior, respiratory, and cardiovascular function, and hERG channel current studies. Journal of Pharmacological and Toxicological Methods, 69(1), 49-60. doi:10.1016/j.vascn.2013.10.005
Miller, Nace, Ayala-Breton C, Steele, Bailey, Peng, & Russell. (2016). Perfusion Pressure Is a Critical Determinant of the Intratumoral Extravasation of Oncolytic Viruses. Molecular Therapy, 24(2), 306-317.
Researchers at AstraZeneca Describe Findings in Hypertension (Quantifying the relationship between inhibition of VEGF receptor 2, drug-induced blood pressure elevation and hypertension). (2018). Health & Medicine Week, 237.