Scientific Overview of Infectious Disease
Increasing world populations and ease of international travel are driving the necessity for better preparedness to protect the public from infectious disease outbreaks. Infectious diseases are caused by pathogenic microorganisms such as bacteria, viruses, parasites or fungi. The U.S. government and many other governments and organizations around the world are engaged to help reduce the prevalence and incidence of these diseases by increasing treatment options.
Basic and applied research methodologies evaluate physiologic changes associated with infections and often include assessment of physiologic parameters or biomarkers such as temperature, fever, heart rate and heart rate variability.
Wireless, implantable telemetry is a proven technology designed for monitoring and collecting data from conscious, freely moving laboratory animals to mimic clinical scenarios determining desirable therapeutic effect.
When comparing diseases in animals with diseases in humans, researchers consider additional information such as time to onset of disease/condition, progression of disease and signs and symptoms of the disease. Physiologic changes lead to characterization of triggers that identify the optimal time for intervention for potential treatment regimens.