The link between metabolism and the cardiovascular system has been getting more attention in the 21st century with the increased rate of obesity and type two diabetes, and their link to cardiovascular disease. Researchers are using animal models to assess early, mid and late stage metabolic diseases, as well as metabolic circadian rhythm and hibernation trends. By adding hemodynamic parameters with metabolic and hibernation studies, researchers are able to assess blood pressure, ECG, blood glucose, temperature and activity in a single animal. The combination of these applications also helps to separate excitement responses due to room entry or food offering, and actual changes in blood glucose.