Myocardial infarction (MI) occurs when the heart muscle is starved for oxygen long enough that cardiac cells die. Researchers studying MI are interested in a number of aspects surrounding the event, including the prevention and treatment of MI. Research questions addressed include:
How to prevent the occurrence of MI
- What markers might be used to predict the event?
- Can life-style changes (diet, exercise etc.) make a measurable difference?
- Are there drug therapies or surgical programs that can prevent MI?
- When to use preventative measures
How to treat MI both during and after the event to limit the extent of the MI damage
- Can the oxygen supply be restored before cell death occurs?
- If cell death occurs, how can the damage be contained?
- Is there a way to repair damaged/dead cardiac cells?
Animal and cellular models are used to study the various aspects of MI. Animal models used to study MI include mice, rats, rabbits and dogs. These animal models may be used as whole animal models , where measurements like pressure, heart rate and electrocardiogram are used as biomarkers of ischemia and MI. Additionally, there are a number of models that employ isolated tissues to study the progression of MI. These isolated systems often need to merge data from multiple sources.
DSI has solutions for all pressure, heart rate and electrocardiograms and also has hardwired solutions capable of combining telemetry with other systems used in tissue research.