The DSI Buxco inhalation exposure system is designed with the ease-of-use desired by researchers new to inhalation exposure, yet providing the performance and flexibility required by the inhalation exposure expert. Unique to DSI is the ability to perform accurate real-time respiration monitoring during exposure, critical for animal welfare and determining accurate deposition levels. With a high degree of port-to-port uniformity, this high efficiency system provides exceptional protocol repeatability, translating into high yield exposure studies. The inhalation tower utilizes an expandable yet compact, “flow-past” design, eliminating rebreathing concerns. The system can be outfitted with a variety of test article delivery devices and instrumentation options for monitoring the towers environment and test article properties.