Buxco Inhalation Exposure System

Whether your study requires general or precise exposure, the Buxco FinePointe system helps you produce better results in less time.

New!: Learn more about subject-specific targeted dosing with SmartStudy


Target AIA in FinePointe 2.9

Nose-Only Inhalation Tower System

  • Develop reproducible results with precise, controlled lung deposition across all subjects with the Accumulated Inhaled Aerosol (AIA) parameter with the addition of plethysmography for collection of respiratory endpoints throughout exposure
  • NEW! With SmartStudy, automatically stop delivery of aerosol to single or multiple-dosage groups when they reach their targeted dose
  • Get the highest quality data with the Buxco system designed to eliminate rebreathing of CO2 and uniform to all open ports
  • Cleaning and maintenance is a breeze with the stainless steel, stackable design.
  • Save time by exposing up to 42 subjects simultaneously
Learn more about the benefits of the FinePointe software platform

Mass Dosing

Buxco Mass Dosing Chambers are used to expose multiple subjects to an aerosol or gas when general dosing can be tolerated.  Benefits of the Buxco chambers include:

  • A perforated floor for for urine drainage
  • Removable lid (no seal, should be used inside a containment hood)
  • Two ports for aerosol or gas delivery
  • Four luer ports for bias flow or other use
  • Ability to hold approximately 15 mice, 6 rats or 2 guinea pigs.
    • The Large Mass Dosing Chamber can hold approximately 25 mice, 10 rats or 4 guinea pigs

Mass Dosing system

Single Subject

The Buxco system offers precise nose-only single subject exposure and general exposure through free roaming tubes.

  • Nose-only: a cost effective version of the inhalation tower, enabling uniform exposure one subject at a time. Single Site Exposure Stations are available for mice, rats, and Hartley guinea pigs.
  • Free-Roaming: single subject exposure for general dosing purposes.
Single Subject Exposure Station , single subject exposure, inhalation chamber, single subject inhalation
inhalation, exposure

Smoke Generation and Delivery

Turn-key options to deliver tobacco or vape smoke to subjects via traditional cigarettes, e-cigarettes, or vape devices.

Smoke GeneratorLR


Multiple Applications and Derived Parameters With One System

Tower & Plethysmograph Derived Parameters

  • View the Tower Derived Parameters Table

  • View Plethysmograph Derived Parameters

Reference Publications

Bosnjak B, Tilp C, Tomsic C, Dekan G, Pieper M, Erb K, EpsteinM. “Tiotropium bromide inhibits relapsing allergic asthma in BALB/c mice.” Pulmonary Pharmacology and Therapeutics. 2014;27:44-51.

Glynn A, Alves D, Frick O, Erwin-Cohen R, Porter A, Norris S, Waag D, Nalca A. “Comparison of
experimental respiratory tularemia in threenonhuman primate species.” Comparative Immunology, Microbiology and Infectious Diseases. 2015;39:13-24

Haapakoski R, Karisola P, Fyhrquist N, Savinko T, Wolff H, Turjanmaa K, Palosuo T, Reunala T, Lauerma A, Alenius H. “Intradermal cytosine-phosphate-guanosine treatment reduces lung inflammation but induces IFN-gamma-mediated airway hyperreactivity in a murine model of natural rubber latex allergy.” American Journal of Respiratory Cellular and Molecular Biology. 2011;44:639-647.