All New SmartStudy: Subject-Specific targeted dosing

Introducing SmartStudy for the Buxco Inhalation System -- a long-sought after technology for improving precision in inhalation research.

Now you can automatically stop delivery of aerosol to single or multiple-dosage groups when they reach their targeted dose. The user defines inhalation exposure targets based on dose amount or time.

Once a subject reaches its targeted dose, inhalation tower port adaptors automatically shut off the flow of compound, and then provide fresh air, allowing the test subject to remain on the tower while other subjects continue to receive dosing.

Rat WBP standard chamber with our wireless EEG/EMG telemetry collection set-up

Induce and Monitor Sleep Apnea

DSI’s Buxco research solutions measure various respiratory endpoints and enable apnea detection within the software platform. Whole body plethysmography (WBP) is the most commonly used solution for obstructive and central sleep apnea research, as it allows the animal to roam freely and sleep naturally. Researchers are able to induce hypoxia and incorporate third party gas analyzers, detect and count apneas, as well as integrate other physiologic collection methods, such as hardwired or wireless EEG/EMG, to assess and correlate sleep parameters with apneic episodes. 

Implantable and External Telemetry for
Cardiovascular and Respiratory Research 

DSI’s telemetry platform allows researchers to measure unstressed physiological endpoints for a more complete picture of whole body responses. Continuously collect endpoints such as ECG, heart rate, blood pressure, left ventricular pressure, pulmonary arterial pressure, respiratory rate, respiratory impedance, pleural pressure, diaphragmatic EMG, and more!

Telemetry is the gold standard technique in whole body preclinical research to monitor baseline physiology with absolute or relative changes. It provides researchers with the most valuable data achievable in acute or chronic studies. Better data comes from monitoring animals in their home cages with little to no handling, decreasing stress response and leading to more reliable data.