DSI Events

Workshop - Guinea pig models of Asthma

Theme: Back to the future - Re-establishing the guinea pig asthma model

The aim of the workshops is to bring together world-leading scientists to explore the possibilities of creating more valid asthma models and appropriate measurements of lung function using the guinea pig. While the guinea pig shares more similarities to humans with respect to physiology, pharmacology and functional responses when compared to the mouse and the rat, there are several challenges that need to be overcome.

The workshop will include seminars concerning the use of the guinea pig for asthma models, lectures, break-out sessions, and the opportunity to view a laboratory demonstration.

Preliminary programme:

Monday 29th May
12.00-12.30 Registration
12.30-13.30 Lunch
13.30-13.40 Welcome – Assoc. Prof. Mikael Adner
13.40-14.10 Physiology/pharmacology in guinea pigs – Professor Brendan J. Canning, Johns Hopkins Asthma and Allergy Center, Baltimore.
14.10-14.40 A guinea pig model of acute and chronic asthma using permanently instrumented and unrestrained animals. Professor Herman Meurs, University of Groningen
14.40-15.10 Acute and chronic asthma models for guinea pigs – Dr William Ford, Cardiff University
15.10-15.40 Coffee and check-in to hotel room
15.40-16.05 Complex role of allergic inflammation in airway hyperresponsiveness – Post-doc Patricia Ramos Ramirez, Karolinska Institutet
16.05-16.30 Guinea pig: (patho)physiology of the respiratory system. Dr Eva Stoffels, Marumoto Veterinary Clinic, Belgium
16.30-17.00 Challenges with lung function measurements - Professor Lennart Lundblad, Vermont University
17.00-17:15 The Industry perspective of model needs- Dr Henric K. Olsson, AstraZeneca
17.15-17:20 Introductions to break-out groups – Professor Sven-Erik Dahlén/Assoc. Prof. Mikael
17.20-19.00 Break-out discussion I
19.30 Dinner

Tuesday 30th May
7:00-8:30 Breakfast and check-out of hotel rooms
8.30-9.10 Guinea pig asthma models for studies of cough – Professor Maria Belvisi, Imperial College, London
9.10-9.40 Human parainfluenza type 3 virus impairs the efficacy of glucocorticoids to limit allergy-induced pulmonary inflammation in guinea-pigs – Dr William Ford, Cardiff University
9.40-10.00 A new HDM-based guinea pig model of asthma – Associate Professor Mikael Adner, Karolinska Institutet
10.00-10.30 Coffee
10.30-11.30 Break-out discussions II
11.30-12.30 General discussion of the outcome from the groups
12.30-13.30 Lunch
13.30-14.30 General discussion of the outcome from the groups, and structure of the paper.
14.30-15.00 Concluding remarks - Mikael Adner, Sven-Erik Dahlén, Gunnar Nilsson


About DSI Events

Data Sciences International (DSI) is involved in over 60 events every year. These include scientific meetings such as industry trade shows, courses and seminars, workshops, as well as educational user groups and symposia all over the world.

DSI supported educational events are scientific meetings organized in cooperation with a local institution or society, pharmaceutical company, university, or local telemetry user group. Educational event meetings serve as an educational forum in which researchers can freely share current scientific information with their peers, students, and other interested scientists.

Common to the general theme of the meetings is the data collected through physiological monitoring of freely moving conscious laboratory animals made possible through the use of fully implantable telemetry technology.

Presentations and posters on the latest methods employed by the presenting researchers enable those attending to benefit from the as yet unpublished work of peers. Presentations can be on a wide range of related research topics including surgical implantation methods, data analysis methods, treatment effects of new pharmaceutical compounds, new animal models, behavioral and physiological interactions, basic research on physiological systems, and numerous other whole animal chronic monitoring research topics.

Meetings are held in classroom style with ample time allowed for questions and discussion among the participants. Typical audience sizes run from 40 to 120.