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Leaders in the Field of Electrophysiology Equipment for Researchers

Multi Channel Systems focuses on the development of precision scientific measuring instrumentation and equipment in the field of electrophysiology for research groups at universities and for the pharmaceutical industry. We provide solutions for extra-cellular recordings with microelectrode arrays in vitro and in vivo as well as for electrical stimulation. Over 20 years of experience and our international distribution network make us the global market leader in the field of non-clinical electrophysiology with microelectrode arrays. Moreover, we offer devices for automated RNA injection and for automated two-electrode voltage-clamp recording of Xenopus oocytes. Because of their modular principle, our products can be extended and adjusted to your specific experimental needs. Apart from their flexibility, our products fit into your laboratories because of their small footprint. 

Highlighted Products


Microelectrode Array (MEA)

The MEA-Systems record, amplify, and analyze signals from biological samples in vitro or ex vivo. The data is analyzed by the included data acquisition software. MEA-Systems are used to record from brain or cardiac slices, neuronal or cardiac cultures, beta cell screening, ex vivo retina, cell lines, or stem cells. Advantages of Multi Channel MEA systems are long-term and repeated recordings, fast results,  unmatched sampling rate of up to 50 kHz per channel, and high-quality, low-impedance microelectrode arrays. Available options include 32 to 252 electrodes, as well as CMOS-Chips with 4225 electrodes, multiwell plates with up to 96-wells, and automated liquid handling for increased accuracy. 






Wireless Optical and Electrical Stimulation

W2100-System_Overview

The wireless in vivo systems are the all-in-one solution for amplifying, recording, and analyzing in vivo data from 4, 8, 16 or 32 channels. The system includes everything you need: Small-sized headstage with integrated A/D converter, digitized transmission, powerful receiver, batteries, as well as a powerful software package.


Click here to learn more about additional product offerings from MultiChannel Systems

MCS Multielectrode Array Publications

Becker S, Vinberg F (2020) Rod phototransduction and light signal transmission during type 2 diabetes. bioRxiv:2020.2001.2014.905265.

Cai H, Li B, Bai A, Huang J, Zhan Y, Sun N, Liang Q, Xu C (2020) Establishing a new human hypertrophic cardiomyopathy-specific model using human embryonic stem cells. Exp Cell Res 387:111736.

Kamar S, Howlett MHC, Klooster J, Graaff W, Csikos T, Rabelink M, Hoeben RC, Kamermans M (2020) Degenerated Cones in Cultured Human Retinas Can Successfully Be Optogenetically Reactivated. Int J Mol Sci 21.

Satir TM, Nazir FH, Vizlin-Hodzic D, Hardselius E, Blennow K, Wray S, Zetterberg H, Agholme L, Bergstrom P (2020) Accelerated neuronal and synaptic maturation by BrainPhys medium increases Abeta secretion and alters Abeta peptide ratios from iPSC-derived cortical neurons. Sci Rep 10:601.

Soscia DA, Lam D, Tooker AC, Enright HA, Triplett M, Karande P, Peters SKG, Sales AP, Wheeler EK, Fischer NO (2020) A flexible 3-dimensional microelectrode array for in vitro brain models. Lab Chip.

Zhong W, Yuan Y, Gu X, Kim SI, Chin R, Loye M, Dix TA, Wei L, Yu SP (2020) Neuropsychological Deficits Chronically Developed after Focal Ischemic Stroke and Beneficial Effects of Pharmacological Hypothermia in the Mouse. Aging and disease 11:1-16.

MCS In vivo Stimulation Publications

Borda E, Ferlauto L, Schleuniger J, Mustaccio A, Lütolf F, Lücke A, Fricke S, Marjanović N, Ghezzi D (2020) All-Printed Electrocorticography Array for In Vivo Neural Recordings. Advanced Engineering Materials n/a:1901.

Deffains M, Haï Nguye403n T, Orignac H, Biendon N, Dovero S, Bezard E, Boraud T (2020) In vivo electrophysiological validation of DREADD-based inhibition of pallidal neurons in the non-human primate. bioRxiv:2020.2001.2003.893610.

Hasbi A, Nguyen T, Rahal H, Manduca JD, Miksys S, Tyndale RF, Madras BK, Perreault ML, George SR (2020) Sex difference in dopamine D1-D2 receptor complex expression and signaling affects depression- and anxiety-like behaviors. Biol Sex Differ 11:8.

Reasmussen D (2020) Effect of Ketamine Treatment on Neuronal Oscillatory Activity in the Nucleus Accumbens and Hippocampus in an Animal Model of Treatment-Resistant Depression.

Cosset E, Locatelli M, Marteyn A, Lescuyer P, Dall Antonia F, Mor FM, Preynat-Seauve O, Stoppini L, Tieng V (2019) Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases. J Vis Exp. 

Iturra-Mena AM, Aguilar-Rivera M, Arriagada-Solimano M, Pérez-Valenzuela C, Fuentealba P, Dagnino-Subiabre A (2019) Impact of Stress on Gamma Oscillations in the Rat Nucleus Accumbens During Spontaneous Social Interaction. Frontiers in Behavioral Neuroscience 13.

Jacob S, Davies G, De Bock M, Hermans B, Wintmolders C, Bottelbergs A, Borgers M, Theunis C, Van Broeck B, Manyakov NV, Balschun D, Drinkenburg W (2019) Neural oscillations during cognitive processes in an App knock-in mouse model of Alzheimer's disease pathology. Sci Rep 9:16363.




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