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Technical Notes

Technical Note No.1 : Performance of the iPRECIO® Pumps.

Flow infusion accuracy of iPRECIO pumps (in-vitro testing). Contents of this technical note is included in the technology page. See Performance of iPRECIO pumps (in-vitro testing) page.

Technical Note No.2 : Recommendation for Long-term infusion.

This technical note outlines best practice implantation for iPRECIO pumps for long term continuous administration.

*Includes recommendation of catheters and couplers.

Technical Note No.3 : SOP for Flow accuracy validations.

Technical note No.3 defines the Standard Operating Procedure (SOP) for flow accuracy validation based on residual/remaining solution in iPRECIO pumps.

Technical Note No.4 : Recommendations for subcutaneous infusion.

Technical note No.4 defines best practice subcutaneous infusion administration site and iPRECIO pump placement and implantation.

Technical Note No.5 : Recommendations for intraperitoneal administration.

Technical note No.5 defines best practice intraperitoneal infusion administration site and iPRECIO pump placement and implantation.

Technical Note No.6 : Recommendations for Intracerebral Administration.

Technical note No.6 defines best practice intracerebral infusion administration site and iPRECIO pump placement and implantation. 322OP: Starter Kit Cranial Infusion Kit for iPRECIO® Pump and 322OP/Kit: Cranial Infusion Kit for iPRECIO® pump are supplied by Plastics One ® (www.plastics1.com).

Technical Note No.7 : Materials Compatibility Kit for iPRECIO® Pump

Technical note No.7 defines the Standard Operating Procedure (SOP) for evaluating the compatibility of vehicle/solvents and agents to iPRECIO®.

Technical Note No.8 : Recommendations for Intrathecal Administration

Technical note No.8 defines the best practice intrathecal infusion administration using iPRECIO® pumps with customized intrathecal catheter part number 0220 from Recathco(www.recathco.com).

Bibliography

Osborn J., presenter; Fink G., discussant
Implantable infusion pumps for chronic rodent studies.
Workshop: Rodent Instrumentation Workshop M. Knuepfer, Experimental Biology, Washington DC.; April 9th to 13th 2011

Yoshinori T.,
Extracellular protein phosphorylation promotes functional recovery from experimental spinal cord injury.
The 6th International Symposium on Receptor Mechanisms, Signal Transduction and Drug Effects
- Development of Novel Therapy to Specific Disease in organ -, Kyoto, Japan; April 1st and 2nd 2011

Schnell C. and Ferrat T.,
Use of novel programmable pump for intracranial administration in an orthotopic glioblastoma tumor model in rats.
DSI User Group Meeting, Paris, France; March 17th 18th 2011

Martel E.
Refined rat pharmacology studies with infusion using implantable pumps.
DSI User Group Meeting, Paris, France; March 17th 18th 2011

Douglas G., Jones H., Edgington A., Saunders K., Neil Morgan S, Pullen N and Parenty G.
GPR54 agonists a way forward for downregulation of the GnRH pathway?
10th International Symposium on GnRH, Salzburg, Austria, Feb 6th -8th 2011

Shobo M., Yamada H., Koakutsu A., Hamada N., Fujii M, Harada K., Ni K., and Matsuoka N.,
Chronic treatment with olanzapine via a novel infusion pump induces adiposity in male rats.
Life Sciences (2011), articles in press, doi:10.1016/j.lfs.2011.02.014[ScienceDirect Link]

Chikara Abe, Kunihiko Tanaka, Chihiro Iwata, and Hironobu Morita
Vestibular-mediated increase in central serotonin plays an important role in hypergravity-induced hypophagia in rats
J Appl Physiol, 2010 Sep 16 [Epub ahead of print]; [PubMed Link]

Yamato M., Okuyama K., Jin GH., Eguchi A., Watanabe Y., Kataoka Y.
Endogenous IL-1β and IL-1 receptor antagonist in the brain are involved in poly I:C-induced immunological fatigue
The 33rd Annual Meeting of the Japan Neuroscience Society, Kobe, Japan., September 2nd – 4th 2010.

Stephanie W. Watts
The Evolving Story of 5-HT and Blood Pressure Mechanisms in a Muddle
Serotonin Club 2010, Montreal, Canada, July 9-11 2010

Susan K. Wood
Insights into pharmacotherapy for co-morbid depression and cardiovascular disease using a rodent model of social stress
iPRECIO® Luncheon Seminar, EB2010, Anaheim, United States, April 20-24 2010

Patrick Davis, Gregory D Fink, Bridget Seitz, and Stephanie W Watts
Serotonin infusion via the iPrecio® micro infusion pump results in repeated reductions in blood pressure in the normotensive Sprague Dawley rat.
FASEB J. 2010 24:lb551 [Abstract in the FASEB Journal]

Jay Gizzi, Theodore Baird, Kyle O'Donohue, Josh Yoder, Jessica Grenwis, and Heather Bogie
Optimization of a fully implantable small animal infusion model involving multi-pressure data collection.
FASEB J. 2010 24:lb571 [Abstract in the FASEB Journal]

Shobo M., Yamada H., Koakutsu A., Harada K., Ni K., and Matsuoka N.
Effect of long-term electrical infusion of olanzapine on fat weight in rats: a novel method for administration of biologically and/or chemically fragile compounds.
The 83rd Annual Meeting of the Japanese Pharmacological Society, Osaka, Japan, March 16th -18th 2010

Abe C., Tanaka K., Awazu H., Morita H.
The role of the vestibular system on the metabolism under hypergravity environment in rats: Implication for motion sickness.
Neuroscience 2009, Chicago, USA., October 17th - 21st 2009.

Yamato M., Okuyama K., Jin GH., Eguchi A., Watanabe Y., Kataoka Y.
Interleukin-1 β expression in the brain is involved in poly I:C-induced immunological fatigue-like behavior in rats
The 32nd Annual Meeting of the Japan Neuroscience Society, Nagoya, Japan., September 16th - 18th 2009.

Coles D.I., Warr A., Mead A.
Characterization of Pentobarbital Physical Dependance and Withdrawal in Rats
9th. Safety Pharmacology Society Annual Meeting, Strasbourg, France., September 15th - 18th 2009.

Infusion Pumps for Small Laboratory Animals
ALN Magazine May/June 2009
http://www.alnmag.com/article/infusion-pumps-small-laboratory-animals

Iwatani C., Yamasaki J., Okahara-Narita J.,Tsuchiya H., Torii R.
Research Center for Animal Life Science Shiga University of Medical Science
Follicular stimulation with micro infusion pump in cynomolgus monkeys (Macaca fascicularis)
The 56th Annual Meeting of the Japanese Association for Laboratory Animal Science 2009, Omiya Sonic City, Japan., May13th - 16th 2009.

Abe C, Tashiro T, Tanaka K, Ogihara R, Morita H.
A novel type of implantable and programmable infusion pump for small laboratory animals.
J Pharmacol Toxicol Methods. 2008 Sep 22. [PubMed Link]

Emiko Matsuoka, Makoto Miyazaki, Kazunori Iwanaga, and Masao Kakemi.
Assessment of Pharmacokinetic-Pharmacodynamic Relationship of Vitamin B12 in the Treatment of Somnipathy in Rats
14th Annual Meeting of Japanese Society for Chronobiology, Tokyo, Japan, November 7-9 2007

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