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Remarkably Sensitive Device Enables New Research Possibilities

DSI now offers a dual pressure transmitter for the precise measurement of various physiologic signal combinations such as:

  • Left ventricular pressure + blood pressure (BP)
  • Pulmonary artery pressure + BP
  • Right ventricular pressure + BP
  • Pleural pressure + BP
  • Bladder pressure + BP, and more!

Scientists seeking greater parameter accuracy (e.g. dP/dt) will find the HD-S21 to be ideal for high-fidelity applications.

Get More Information Earlier, with Less.
A more complete physiologic assessment from a single animal is possible with the
HD-S21:

  • Reduced inter-animal variability
  • Reduced cost (labor, compound, housing)
  • Early risk assessment
  • Integrate with additional parameters (metabolic, renal)

Eliminate variability associated with collecting a single pressure from two separate animal groups (chronically or acutely), all from conscious, freely-moving animals.

Other Important HD-S21 Benefits:

  • New catheter design offers precise detection of key pressure signal attributes
  • Excellent pressure channel stability
  • In addition to pressure, collect a biopotential,
  • temperature and activity data!

 

 

 

 

Eliminate variability associated with collecting a single pressure from two separate animal groups (chronically or acutely), all from conscious, freely-moving animals.
Left ventricular pressure, arterial blood pressure and electrocardiogram data example shown. Temperature and activity are also simultaneously collected.

 

Digital Data Simplifies Study Management

  • auto-loading of calibration data reduces configuration time and eliminates data entry error
  • animal ID ensures data collection is from the intended animal
  • battery ON-time counter helps track study duration and remaining battery life

Built to Last
The HD-S21 features a hermetic electronics packaging design to prevent moisture ingress among device components.

HD-S21 Specifications
Appropriate Animal Models Rats, ferrets, marmosets, guinea pigs and more.
Weight 8 grams
Volume 5.9 cc
Minimum Animal Weight 175 grams
Maximum Cage Size* 42 X 42 X 18 cm
Battery Life Warranted For 2 Months
Implant Duration Warranted For 9 Months
Parameters Measured Two pressures, biopotential, temperature, activity, battery ON time and battery voltage
Temperature Operating Range 34 To 41 degrees Celsius
On-Off Mechanism Activated by holding a magnet near the device for 2 seconds while confirming with presence of tone with radio tuned to low end of AM band.
Software Compatibility Dataquest A.R.T. 4.3, OpenART 4.3, Ponemah 5.0
Hardware Compatibility Compatible with existing DSI Physiotel* Hardware
Pressure Channel Specifications
Pressure Range -20 To 300 mmHg
Catheter Length Options 8, 10 or 15cm
Ambient Pressure Range 670 To 800 mmHg
Initial Accuracy ± 3 mmHg
Pressure Channel Drift <2mmHg/month (Maximum); -0.25mmHg/month (Average)
Frequency Response 8cm catheter†: >100Hz (Minimum Performance), 120Hz (Average Performance)
Biopotential Channel Specifications
Biopotential Input Range ±5mV
Biopotential Input Bandwidth 0.1-145 Hz
Biopotential Lead Length 30 cm or 60 cm
Digital Data Information
Battery ON Time Track study duration and device use; accurate within ± 1.5 days at body temperature (i.e. -37°C)
Animal ID (serial Number) Transmission of ID to assigned receiver prevents wrong data collection
Calibrations Simplifies configuration and ensures accurate calibration entry


*Multiple receivers can be used to provide coverage for cages of larger dimensions.
†Recommended catheter length for small animal LVP applications.

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