Calculate Absolute Ventricular Volume
Advantage Brochure PDF
Admittance versus Conductance PDF
The ADVantage™ Technology Benefits
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The ADVantage™ system is the first technology to output true ventricular volumes in real-time. The system does not require an injection of hypertonic saline “bolus” to measure ventricular volume. Having to use a “bolus” can be time-consuming and an error-prone calibration procedure. Now, a new technology from Scisense called the ADVantage™ system, uses “admittance” measurements to achieve an even higher degree of accuracy without the need for a saline bolus technique. Lower standard deviations are the end result, which ultimately means fewer animals are used, costs to run a study are greatly reduced and data can be published faster.
How the ADVantage™ System Works
Admittance technique measures both conductive and capacitive properties of blood and muscle. The basis of measuring admittance instead of conductance is that at frequency ranges of about 20 kHz, blood is purely resistive and has no measurable capacitance, but muscle has both capacitance and resistance properties. This allows separation of the admittance of the muscle from the admittance of blood, using electric field theory.
Common Applications for Pressure-Volume Studies Include
- Heart Failure
- Ischemia/Reperfusion Injury
- Cardiac Hypertrophy
- Myocardial Stunning & Infarction
- Cardiovascular Remodeling
- Stem Cell Research
- Phenotyping
- Pharmacology & Toxicology
- Valve Disease
- Gene Therapy
ADVantage Pressure-Volume Control Unit Features
- Digital interface
- 15 push-button keypad for data entry and function selection
- 4 independent push-button controls for pressure offset
- 4-line multi parameter back-lit LCD
- Ability to read and store factory calibration settings from PV catheters and surface probes
- 4 real-time, optically isolated outputs
- Pressure
- Admittance Magnitude (|Y|) or Conductance (G)*
- Phase Angle
- Absolute Volume
- Multi-level menus with user-friendly prompts for catheter calibration and data collection
- Works seamlessly with the Ponemah data acquisition system
Better Data. Better Science. Better Service.
DSI offers a complete research solution, from signal to summary, with the Ponemah System. The Ponemah System is a multi-application platform, which utilizes state-of-the-art digital technology to automate the data analysis routinely performed in physiology, pharmacology and toxicology laboratories. The Ponemah software architecture is modular in nature and allows the user to custom design the configuration based on their needs, budget and convenience – without the need for any programming.
Researchers can now get a complete system, through one source, and receive the same high level of customer support and service that DSI has offered for more than 20 years.
Contact your local DSI Technical Representative to learn more about the benefits of DSI products and the ADVantage™ system.