DSI has recently created a Case Studies section to our website. Check back often to see the most recent additions to this page.
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iPRECIO®– 5-HT Administration - This study demonstrated with an iPRECIO® pump that a smaller rate of 5-HT than previously employed elicits a hypotensive effect in S.D. rats. |
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New CNS Models in Safety Pharmacology - In this study, video-EEG monitoring proved to be useful in characterizing neurological adverse effects with unpredictable onset, and computerized video-EEG analysis was used for preconvulsant risk assessment, spectral analysis of frequency bands, and sleep stage determination. |
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Jacketed External Telemetry (JET) - This qualitative study compares ECG data captured simultaneously from implantable telemetry and JET on the ET2 platform in six male beagle dogs. |
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Novel Safety Pharmacology Multiparameter Model - This study demonstrates the utilization of a novel automated blood sampling and telemetry (ABST) system for acquisition of multiple PD endpoints with simultaneous PK sampling in response to compound X in the same group of animals. |
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Chronic Pleural Pressure Measurement - A novel procedure using a fluid filled catheter attached under the serosal layer of the esophagus enabled chronic pleural pressure measurement. |
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iPRECIO- ANG II Administration Comparison - This study tested the iPRECIO® pump in a chronic subcutaneous angiotensin II infusion protocol run in conscious adult rats to produce chronic hypertension. |