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Biodefense

The need for bioterrorism countermeasures as part of the defensive arsenal for a modern society has prompted extensive scientific research in a variety of areas.  As a result, more than 60 identified biothreats are currently being addressed in US government funded research programs.  Subsequently, academic and industrial institutions alike have increased the number of BSL-3 & BSL-4 facilities under construction to meet research demands.  Naturally, telemetry has become integral in the success of this research as investigators seek to maximize animal models, analyze and report data efficiently and mitigate potential personnel risk.  As a long time solution provider to government researchers and related contract facilities, DSI has become a trusted consultant to entities seeking to construct Bio Safety Labs, instrument them appropriately and ultimately enable study success!

Sensors
According to the animal rule guiding model development in biodefense research, more than one species might be needed if appropriate characterization is not obtained with one model.  DSI is currently the most experienced telemetry provider to offer a robust telemetry platform adaptable to usage across species ranging from mouse to minipig.

Implantable Telemetry
Wireless physiological monitoring has established its position as a technology that enhances worker safety while providing conscious subject chronic data.  DSI transmitters are fully implantable and require minimally invasive to invasive surgery depending on the physiologic parameters of interest.  Historically, surgery has not been a barrier to usage and DSI provides many options to assist users in acquiring the appropriate skills for success.  Implantable technology enables researchers to acquire data on ambulatory models that closely represent human scenarios; thus, providing critical physiologic data not feasible via other methods. 

External Telemetry
Studies amenable to external monitoring solutions are supported by our jacketed external telemetry, (JET).  DSI’s JET platform enables researchers to obtain critical physiologic information in a flexible and accurate platform that includes ECG, respiratory and blood pressure parameters.

Data Acquisition & Analysis
Access to data from acquisition to reporting is crucial to study design and success. Our software solutions enable researchers to implement complex study designs covering multiple subjects in single or multiple rooms.  DSI provides options in relation to study complexity and investigator need.  The Ponemah software platform is validated in pharmacology and toxicology labs worldwide and uniquely provides continuous data storage and experimental analysis either as they occur on study or during subsequent review.  Operating within GLP guidelines, the Ponemah platform is designed for the researcher whose protocol demands flexibility while maintaining accuracy, in a validated environment. The Ponemah software is modular, allowing users to custom design the configuration based on their application, budget and convenience—without any programming.

Useful Offering for Biodefense Studies:

DSI Sales and Service
A telemetry innovator, DSI has experience supporting research across many disciplines for over two decades.  Headquartered in St. Paul, DSI supports a global research community through a dedicated field sales force that spans the United States, Europe and China. 

Technical Support
Our technical support team consists of field experienced research scientists and engineers dedicated to understanding DSI technology in relation to existing and developing protocols.  Staffed to support our telemetry and acquisition and analysis functions, our support team works together to ensure researchers maintain study timelines and achieve study goals.

Customer Service
Our dedicated customer service department is also a regionally located function, solidifying the customer experience from initial contact through daily product usage.  DSI has only your research success in mind!

Surgical Services
Our experienced surgical services group provides model instrumentation education in many formats.  Detailed surgical videos and manuals provide pertinent information geared toward increasing success for the novice telemetry user.  Contact DSI to learn more about your options regarding hands on education provided by our experienced surgeons.

Links to agencies involved with Biodefense